Fragile X syndrome is a genetic disorder, which is due to a mutation
in the X-linked FMR1 gene that causes a range of developmental problems
including learning disabilities and cognitive impairment or intellectual
disability. Males with fragile X syndrome almost always exhibit mental
retardation, usually in the moderate range, and often have characteristic
physical features and behaviour. Since the mutation is X-linked, males are more
severely affected than females.
Prevalence:
In general population Fragile X syndrome occurs in
approximately 1 in 4,000 (1:4000) males and 1 in 8,000 (1:8000) females.
Signs and symptoms of Fragile X syndrome:
